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For decades, psychiatry has focused on initiating treatment—which medication to prescribe, in what dose, and for how long. But what happens when treatment needs to stop? How a medication is stopped is just as important as how it is started, and abrupt discontinuation can lead to unnecessary suffering, relapse, and often preventable withdrawal symptoms. Based on the principles of the bestselling Stahl's Prescriber's Guide, this essential resource provides user-friendly guidance on deprescribing or switching psychotropic medications safely and effectively. 64 medications are presented in a consistent format to facilitate rapid access to deprescribing information. Divided into color coded sections, the book allows the reader to identify key details about when and why to deprescribe, the risks and mechanisms of withdrawal, tapering protocols, cross-titration strategies, and how to distinguish withdrawal symptoms from relapse. Evidence-based recommendations and expert clinical insights make this a must-have manual for all psychiatric prescribers.